THC Prevents Colon Cancer, According To New Study

The body of evidence pointing to the anti-cancer properties of cannabis continues to expand at a rapid rate, with new research indicating that THC prevents tumours from forming in the colon by blocking inflammation. Appearing in the journal iScience[i], the new study builds on previous research which has illustrated how the anti-inflammatory effects of certain cannabinoids help to curtail chronic digestive illnesses like Crohn’s disease, colitis and inflammatory bowel disease (IBD). Related Post CBD Kills Cancer Cells But Leaves Healthy Cells Untouched Many of these disorders are caused by excessive inflammation in the colon, as the body’s immune system releases a glut of inflammatory proteins known as cytokines. While this response is necessary to remove pathogens and heal injuries, it can sometimes spin out of control, causing damage to surrounding tissue and sparking the formation of tumours. Several of these cytokines have been strongly linked to colon cancer, with a protein called Interleukin-22 (IL-22) among the main culprits. In order to investigate the therapeutic action of THC, the study authors injected mice with a carcinogenic compound that is known to cause cancer by triggering the release of excessive amounts of cytokines in the colon. When these mice were treated with THC, however, inflammation was reduced and tumours were prevented from forming. A more detailed analysis revealed that this response was mediated via the CB2 receptors present in the rodents’ digestive tracts. By binding to this receptor, THC caused certain immune cells known as antigen-presenting cells (APCs) to change their behaviour…

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