Clinical Trial: Oral THC Administration Associated with Opioid-Sparing Effects
Trauma patients administered oral THC consume fewer opioids than do similarly matched controls, according to clinical trial data published in the journal Trauma Surgery & Acute Care. Investigators affiliated with the Saint Anthony Hospital and Medical Campus in Colorado assessed the impact of the off-label use of dronabinol (FDA-approved synthetic oral THC) on opioid consumption patterns in trauma patients with acute pain. Sixty-six patients participated in the study. Half of the participants received dronabinol and the other half did not. Authors reported that patients administered oral THC experienced a “nine-fold greater reduction in opioid consumption” compared to controls. These opioid-sparing…
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