Clinical Trial Finds Cannabis Oil is Well-Tolerated, Effective Insomnia Treatment

Clinical Trial Finds Cannabis Oil is Well-Tolerated, Effective Insomnia Treatment
HIghtimes main

Many will attest, alongside myriad additional studies, to the sedative, relaxing qualities of cannabis as a sleep aid. Now, a new study published in the Journal of Sleep Research adds additional insight surrounding the benefits of cannabis for treating insomnia, finding that the short-term use of plant-derived cannabis extracts is well-tolerated and effective for patients diagnosed with insomnia. Insomnia involves difficulty falling or staying asleep and is relatively common, experienced by up to 30% of the general population. In their introduction, the authors point to the potential for cannabis to help alleviate sleep dysfunction along with the impact of individual cannabinoids on sleep. Specifically, they reference the sedative effect of THC and the potential of CBD as a sedative in higher doses. The trial looked to assess the tolerability and effectiveness of medicinal cannabis oil on sleep in adults with insomnia. The study was conducted between May 2020 and May 2021 at the National Institute of Integrative Medicine in Melbourne, Australia. Researchers assessed the use of a cannabis oil product, versus placebo, in 29 subjects with chronic insomnia.  Each extract contained 10mg of THC and 15mg of CBD per milliliter, along with a lesser amount of other cannabinoids and naturally occurring terpenes, and each participant consumed either the extract or a placebo for a two-week period. Participants were instructed to take the oil in the evening with food, increasing their doses by 0.1ml (1mg THC/1.5mg CBD) increments each day, starting with 0.2ml on the first day and maxing out at 1.5ml (15mg HC/22.5mg CBD). The six-week study consisted of a one-week run-in period, a two-week intervention period, a one-week wash-out period and a second two-week intervention period, with four total assessments taken at the start and completion of each intervention phase. Primary outcome measures included saliva midnight melatonin levels and…

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Source : Clinical Trial Finds Cannabis Oil is Well-Tolerated, Effective Insomnia Treatment

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