Fentanyl Overdose Reversal Drug Stronger Than Narcan Released

Fentanyl Overdose Reversal Drug Stronger Than Narcan Released
High Times

A new overdose reversal drug is arming first responders with a more powerful tool for fentanyl overdoses. Zimhi—an FDA-approved high-dose naloxone injection—was recently released for the treatment of fentanyl overdoses. It delivers a higher, intramuscular immediate dose of naloxone, a higher dose than Narcan. Narcan, the common brand name of naloxone, an opioid antagonist, has saved lives by reversing the effects of an opioid overdose in spray form. But even Narcan is no match for fentanyl, in some cases. A stronger antidote was needed. US WorldMeds, a pharmaceutical company, announced the release of Zimhi in a press release, and highlighted a specific event: Clinical counselor Charles Pemberton regularly carried a trauma bag in his truck which contained naloxone. When Pemberton saw a driver passed out at a fast-food restaurant drive-thru in front of him, he administered two doses of naloxone, and probably saved that person’s life. “At that moment, all my training kicked in,” Pemberton said. “It wasn’t until later that I felt relief that I had naloxone on hand.” Pemberton added that substance abuse issues tend to come up during the holidays. “Make sure to ask questions and listen, but don’t lecture,” Pemberton said. The National Institute on Drug Abuse reports that opioid overdose deaths continue to rise annually—primarily with fentanyl. Over 107,000 people in the United States died from a drug overdose in 2021, usually involving opioids. The DEA reports more overdoses are happening as criminals mass-produce fake pills containing fentanyl that mimic other pills. Adamis Pharmaceuticals Corporation developed Zimhi. It can be used on the fly—rapidly pulling off the cap and inserting the needle into the thigh. “Naloxone is an opioid antagonist that is used to temporarily reverse the effects of an opioid overdose, namely slowed or stopped breathing,” the U.S. Surgeon General Jerome Adams said. “Expanding…

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