The cannabinoids and terpenes with anti-inflammatory potential

The cannabinoids and terpenes with anti-inflammatory potential
Cannabis Health News

A study published earlier this month highlights the anti-inflammatory potential of a number of potent cannabinoids and terpenes.  New research has highlighted the potential of selected cannabinoid and terpenes to reduce inflammation associated with a range of serious health conditions.  The study, which was co-published by biopharmaceutical research and development company, Gb Sciences in the journal Food and Chemical Toxicology is said to be among the first to demonstrate the anti-inflammatory potential of some of the minor components of cannabis. Finding cannabis compounds with anti-inflammatory properties may be useful in decreasing inflammation associated with a wide range of serious human disorders. This has become even more important due to the increasing prevalence of chronic and auto-immune inflammatory disorders. Autoimmune diseases, which include conditions such as type 1 diabetes to rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis are now estimated to be increasing by up to 9% a year. Those behind the study believe the compounds found in cannabis could have more favourable side effect profiles than commonly prescribed NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). How the study worked  The specific compounds included in this study were chosen based on their prior activity within chemovar studies.  To determine whether these cannabinoids and terpenes could reduce inflammation, Gb Sciences’ colleagues at Michigan State University tested the individual cannabis constituents over a wide range of concentrations in human, primary immune cells in a co-culture system that mimics the complex interactions that regulate the human immune system.  Three immune cell types were chosen as representatives within these native human immune cell mixtures based on their important roles in modulating the inflammatory cascade. Which cannabinoids had greater anti-inflammatory potential? This study demonstrated that delta-9 tetrahydrocannabinol (THC) had the greatest effect on reducing inflammatory biomarkers and processes in all three immune cell types.  Following THC, the greatest…

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