Israeli Company to Unveil Psilocybin Nasal Spray System

Israeli Company to Unveil Psilocybin Nasal Spray System
High Times

Israeli biopharmaceutical company Madrigal Mental Care will unveil novel nanotechnology to deliver psilocybin via nasal spray for the treatment and prevention of post-traumatic stress disorder (PTSD) at Biomed Israel 2022, on May 10-12, 2022, at the David InterContinental Hotel in Tel Aviv, Israel, according to a May 9 press release. Biomed Israel is a broad celebration of the life science and technology industries. At past events, the event attracted over 6,000 attendees, with 1,000 attending internationally from over 45 countries. The novel nasal spray system enables nose-to-brain delivery of organic nanoparticles that encapsulate molecules of psychedelic substances—in this case, psilocybin. This nasal spray delivery system can also be used to deliver ketamine, mescaline, MDMA, and other psychedelics. The nanotechnology was invented by Prof. Amnon Sintov, Department of Biomedical Engineering at Ben-Gurion University of the Negev (BGU) with licensing from BGN Technologies, the Technology Transfer Company of BGU. “An increasing number of studies point to the advantages of using psychedelic drugs for the treatment of psychiatric disorders such as PTSD, depression, anxiety, obsessive compulsive disorder, and even addiction, with low doses,” Professor Sintov said. “Due to their powerful effect on the human brain, it is imperative to be able to deliver these drugs in a safe manner and in precise doses. Our novel nanotechnology platform enables encapsulation of precise drug doses in nanoparticles that are delivered directly to the brain via an intranasal spray, in a very efficient, fast, and safe manner.” An increasing number of studies are exploring the use of psilocybin for the treatment of depression, end-of-life care, and PTSD. Since psilocybin is an 5-HT2A agonist, it’s being explored for its usefulness in many of these areas. The brain’s cortex is full of 5-HT2A receptors–notably in areas that control reflection, imagination, and introspection. “Our technology ensures a focused and…

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Source : Israeli Company to Unveil Psilocybin Nasal Spray System

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