Whole-Plant Cannabis Extract Reduces Epileptic Seizures By 86% in Small Study

High Times

A small study of children with treatment-resistant epilepsy has found that whole-plant cannabis therapies reduced seizures by 86 percent, according to research published recently by the journal BMJ Paediatrics Open. To conduct the study, researchers collected retrospective clinical data from caretakers and clinicians of 10 children with intractable, or drug-resistant, epilepsy. All 10 patients recruited for the study had not responded to CBD products. When the patients were given a whole-plant cannabis oil containing THC, CBD, and other cannabinoids as well as compounds including terpenes and flavonoids, the frequency of their seizures decreased by nearly 90 percent. “Seizure frequency across all 10 participants reduced by 86 percent with no significant adverse events,” the authors of the study wrote.  The dosage of cannabis oil was determined by each patient’s physician. On average, the children in the study received about 5mg of THC per day, although they did not get high from the medication. Parents reported results to researchers by phone or via video conference calls. Few adverse effects, including excessive tiredness before exact dosing was determined, were reported to researchers. “All parents reported that the whole-plant products were well-tolerated and the children showed improvements in their mood, behavior, eating anding as well as substantial improvements in their cognitive [mental] abilities,” said study author Rayyan Zafar, a fellow at the Centre for Psychedelic Research and Neuropsychopharmacology at Imperial College London. The research also revealed that using the cannabis oil resulted in a dramatic reduction in the number of other medications taken by the patients in the study. At the onset of the research, patients were taking multiple medications daily, a figure which declined significantly after treatment with cannabis oil was begun. “Participants reduced use of antiepileptic drugs from an average of seven to one following treatment with medical cannabis,” the researchers wrote.…

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Source : Whole-Plant Cannabis Extract Reduces Epileptic Seizures By 86% in Small Study

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