Virpax Signs Agreement with Sinclair Research to Initiate Investigational New Drug (IND)-Enabling Studies for AnQlar™


BERWYN, Pa.–(BUSINESS WIRE)–#pharma—Virpax® Pharmaceuticals Inc. (“Virpax” or the “Company”) (NASDAQ: VRPX), a company specializing in developing product candidates for pain management, CNS disorders and anti-viral indications, signed an agreement with Sinclair Research, a leading provider of nonclinical research services, to initiate preclinical studies of AnQlar™. AnQlar is being developed by Virpax as a daily over-the-counter (OTC) prophylactic product for treatment against SARS and influenza. Under the terms of this agreement, Sinclair Research will perform preclinical animal studies including method, dosage and toxicity as part of the enabling trials for an Investigational New Drug Application (“IND”) for AnQlar, as required by the U.S. Food and Drug Administration (“FDA”). The studies are expected to begin in January of 2022. “This agreement represents another significant step in the expedited commercialization pathway for AnQlar and is an important milestone in the development of our anti-viral pipeline. With the additional funding recently secured by Virpax and the strengthening of our balance sheet, we are continuing to advance our product candidates and to move them through preclinical studies and into human clinical trials,” said Anthony Mack, Chairman and Chief Executive Officer of Virpax Pharmaceuticals. About AnQlar™ AnQlar (GCPQ) is a chitosan derivative and is a positively charged molecule that binds electrostatically to negatively charged coronaviruses. AnQlar can prevent the binding of coronavirus to the ACE-2 receptor on the cell surface that mediates viral infection. This molecule may have two mechanisms of action: viricidal properties and prevention of entry into cells via the ACE-2 receptor. AnQlar is also a mucoadhesive with a prolonged nasal residence time and may be a molecular barrier to viral infection by inhibiting such binding by nasal application. Preliminary in-vitro, ex-vivo, and in-vivo data demonstrated that AnQlar inhibits replication of SARS-CoV-2 and may inhibit viral spread as well as viral brain load at…

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Source : Virpax Signs Agreement with Sinclair Research to Initiate Investigational New Drug (IND)-Enabling Studies for AnQlar™

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