The Cannabinoid Three Times Stronger Than THC

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Legal ambiguities surrounding THC analogues have precipitated a rise in popularity among certain cannabinoids over the past few years. Accordingly, interest in a little-known compound called THC-O-acetate has spiked recently. Said to be three times more potent than THC, this rare cannabinoid is purported to produce psychedelic-like effects. However, with few verifiable accounts of its properties, large gaps remain in our understanding of this enigmatic substance. Related Post What Is Delta-8-THC? What Is THC-O-Acetate? As its name suggests, THC-O-acetate shares a chemical structure with THC but has an acetate group attached. According to some sources, this added feature allows the compound to penetrate certain barriers in the digestive tract and the brain, thus potentiating its effects. Technically speaking, THC-O-acetate is a metabolic prodrug, meaning it only becomes psychoactive after being metabolised. In this case, the body must “de-acetate” the molecule by removing the acetate group to potentiate the compound. Much of what we know about THC-O-acetate stems from research carried out by the US military between 1948 and 1975. In an attempt to determine whether or not the molecule could be weaponised as a non-lethal incapacitating agent, army researchers measured its effects on dogs. Results suggested it impairs muscle coordination about twice as much as regular THC. Data regarding the effects of THC-O-acetate in humans, however, is pretty scarce. According to certain sources, the compound is 300 percent more potent than THC and generates trippy experiences similar to those occasioned by psychedelics. However, this has not been widely corroborated. This lack of information is largely because THC-O-acetate is not easy to manufacture and is not readily available. Creating the molecule involves using highly corrosive, flammable, and explosive solvents, all of which must be handled under laboratory conditions. The result is a heavy brown oil devoid of terpenes, flavonoids, or other…

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