Researchers Develop Test to Determine Cannabinoid Dominance in Cannabis


<![CDATA[George Weiblen, a professor in the College of Biological Sciences at the University of Minnesota and the science director and curator of plants at the Bell Museum, has been working since 2002 to discover the genetic differences between hemp and marijuana.He’s recently cracked a major component of the code. A research team led by the Weiblen Lab has developed a genetic test that can predict whether cannabis will produce mostly cannabidiol (CBD) or tetrahydrocannabinol (THC), having broad implications on both cannabis and hemp industries.The team’s findings were recently published in the American Journal of Botany.While Weiblen acknowledges that other similar tests have been developed, the University of Minnesota’s research and test delve deeper into the biology and mechanisms behind why the test works. In other words, they’ve discovered on the molecular level why certain cannabis produces more CBD and vice versa for THC.“We are looking at the genes that are ultimately responsible for the pattern we see,” Weiblen tells Cannabis Business Times and Hemp Grower. “What we’ve done is proven our model across lots of different kinds of cannabis, from industrial hemp to medicinal cannabis to feral ditchweed [wild hemp].”How it WorksWeiblen says across all types of cannabis, a small area of their chromosomes determines whether the plant will be one of three types: CBD-dominant, THC-dominant or intermediate with approximately equal levels of each.The team found these consistencies by studying more than 350 different samples of cannabis. (The Weiblen Lab has a DEA research registration and obtained drug cannabis from the National Institute on Drug Abuse.)The lab test developed by the research team homes in on one gene: the gene for CBD. This gene has two variations that result in it either producing CBD or failing to produce CBD, Weiblen says. Those variations are different sizes on the chromosome, so…

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Source : Researchers Develop Test to Determine Cannabinoid Dominance in Cannabis

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