The Curious Case of CBD-Dopamine Paradox

Cannabis Radar

Marijuana consumption may momentarily enhance your body’s dopamine level and neuron activity. But the euphoria and the overwhelming excitement you are experiencing is only temporary – the result of acute marijuana intake. Research shows that long-term cannabis use not only disrupts your normal dopamine levels, but it is “associated with blunting of the dopamine system”, thereby causing many disorders and medical conditions. Besides, soon after the euphoria of the first-time use, cannabis withdrawals cause a sudden drop in dopamine levels. If you’re wondering which substance in marijuana causes such euphoria – but only to snatch it away – you probably haven’t heard of Δ-9 tetrahydrocannabinol or THC. This is the key psychotropic chemical component of cannabis plants – that includes both marijuana and hemp. The only difference is that marijuana has more of the THC – giving you a “high” and making it illegal, while hemp has more of CBD, keeping THC levels as low as 0.3% by dry weight. CBD & Dopamine: A “Joint” Effort Cannabidiol (CBD), on the other hand, is a non-addictive component of cannabis that impacts our endocannabinoid system (ECS) through the body’s cannabinoid receptors. Its impact on the ECS isn’t quite like the THC – the only other key component of Cannabis plants. The ECS works conjointly with the Central Nervous System (CNS) and parts of the Peripheral Nervous System (PNS) to carry out a series of functions. The key role of the ECS is to maintain, regulate, and restore chemical and physiological balance within the body – in short, to maintain homeostasis. Scientific research and clinical trials have portrayed the different ways that CBD has helped the ECS achieve this. To do that, it often helps alleviate symptoms of many ailments and relieves the person from the agony he is suffering due to his…

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Source : The Curious Case of CBD-Dopamine Paradox

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