What happens when you green out?

Marijuana.com

It wouldn’t be unfair to say that 2020 has been one hell of a year, and the need to escape from reality — if even for a few hours — is more tempting than ever. Consuming cannabis can be good for what ails you in so many ways, from its medicinal compounds that could help calm inflammation and contribute to a better night’s sleep, to its ability to bring a feeling of euphoria that could take your mind momentarily off of the world’s troubles.  For all the myriad benefits of cannabis consumption, there can be a few downsides, especially for novice consumers, including the dreaded “green out.” Defined as an experience caused by consuming too much cannabis, signs of a green out include nausea, sweating, dizziness, vomiting, severe anxiety, increased heart rate, reduced blood pressure, and even mild hallucinations.  While the research is still out as to what precisely causes a green out, anecdotal accounts from consumers and doctors hold that THC — the psychoactive cannabinoid responsible for the high you feel while consuming — accountable.  Greening out and the endocannabinoid system All mammals have an endocannabinoid system (ECS), composed of endogenous (internal) endocannabinoids, enzymes, and receptors. Humans often ingest exogenous (external) cannabinoids through cannabis consumption, most famously the non-intoxicating CBD and the aforementioned THC. But humans also produce two endocannabinoids on their own; anandamide and 2-arachidonoylglycerol.  Both endogenous and exogenous cannabinoids bind to CB receptors called CB1 and CB2. These receptors are located throughout the body, including skeletal tissues, internal organs, and the skin to help create bodily harmony, or homeostasis. When your body is out of whack in some way, let’s say it needs to respond to a change in outside temperature for example, the ECS rounds up endogenous cannabinoids to help bring your body back to balance. …

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