There have been quite a few other studies taking a deeper look into what happens when people mix pot and coffee. The latest study, released last year and published in the Journal of Internal Medicine, revealed that our metabolism has much to do with the effects of cannabis and coffee. Specifically, they found that when we consume more coffee, this results in a reduction of blood metabolites within our endocannabinoid system (ECS). As we know, the ECS plays an important role in regulating many body processes such as our sleep, appetite, mood, and more.
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Source : What Really Happens When You Combine Cannabis and Coffee in the Morning?
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